Emergence of serogroup C meningococcal disease associated with a high mortality rate in Hefei, China

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Emergence of serogroup C meningococcal disease associated with a high mortality rate in Hefei, China

BACKGROUND Neisseria meningitidis serogroup C has emerged as a cause of epidemic disease in Hefei. The establishment of serogroup C as the predominant cause of endemic disease has not been described. METHODS We conducted national laboratory-based surveillance for invasive meningococcal disease during 2000-2010. Isolates were characterized by pulsed-field gel electrophoresis and multilocus seq...

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Recent emergence of serogroup C meningococcal disease in Greece.

The number of cases of meningococcal disease reported to the Meningitis Reference Laboratory in Athens rose dramatically in 1996-1997. The aims were (1) to determine if the increase was due to introduction of new strains, (2) to assess the geographic and age distribution of the cases, (3) to compare antibiotic sensitivity patterns of the current isolates with strains from the early 1990s. In 19...

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Meningococcal disease serogroup C

Despite current advances in antibiotic therapy and vaccines, meningococcal disease serogroup C (MDC) remains a serious threat to global health, particularly in countries in North and Latin America, Europe, and Asia. MDC is a leading cause of morbidity, mortality, and neurological sequelae and it is a heavy economic burden. At the individual level, despite advances in antibiotics and supportive ...

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ژورنال

عنوان ژورنال: BMC Infectious Diseases

سال: 2012

ISSN: 1471-2334

DOI: 10.1186/1471-2334-12-205